PURPOSE OF REVIEW: To familiarize the reader with the concept of precision medicine in food allergy through the most recent insights in the diagnosis, prognosis, and management of the disease. RECENT FINDINGS: With the advent of omics sciences, a new era is commencing. Food protein allergens characterization and quantification together with the immunoglobulin E epitope mapping will contribute to the diagnosis/prognosis of food allergy and will lead to a better safety assessment of foods. The characterization of biomarkers able to identify specific phenotypes and endotypes will improve the diagnostic accuracy. This together with a better understanding of mechanisms of action of the different therapeutic options will allow the accurate selection of the appropriate patient. SUMMARY: In the near future, advances in technologies and data interpretation will allow a better understanding of the pathogenesis of food allergy and the development of a personalized treatment tailored on the specific patient' profile.

Precision medicine in food allergy / Arasi, S.; Mennini, M.; Valluzzi, R.; Riccardi, C.; Fiocchi, A.. - In: CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY. - ISSN 1528-4050. - 18:5(2018), pp. 438-443. [10.1097/ACI.0000000000000465]

Precision medicine in food allergy

Mennini M.;
2018

Abstract

PURPOSE OF REVIEW: To familiarize the reader with the concept of precision medicine in food allergy through the most recent insights in the diagnosis, prognosis, and management of the disease. RECENT FINDINGS: With the advent of omics sciences, a new era is commencing. Food protein allergens characterization and quantification together with the immunoglobulin E epitope mapping will contribute to the diagnosis/prognosis of food allergy and will lead to a better safety assessment of foods. The characterization of biomarkers able to identify specific phenotypes and endotypes will improve the diagnostic accuracy. This together with a better understanding of mechanisms of action of the different therapeutic options will allow the accurate selection of the appropriate patient. SUMMARY: In the near future, advances in technologies and data interpretation will allow a better understanding of the pathogenesis of food allergy and the development of a personalized treatment tailored on the specific patient' profile.
2018
biomarkers; food allergy; omics; precision medicine; system biology; Allergens; Cross Reactions; Desensitization, Immunologic; Dietary Proteins; Epitope Mapping; Food Hypersensitivity; Humans; Immunoglobulin E; Phenotype; Prognosis; Proteomics; Precision Medicine
01 Pubblicazione su rivista::01a Articolo in rivista
Precision medicine in food allergy / Arasi, S.; Mennini, M.; Valluzzi, R.; Riccardi, C.; Fiocchi, A.. - In: CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY. - ISSN 1528-4050. - 18:5(2018), pp. 438-443. [10.1097/ACI.0000000000000465]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1314460
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 6
  • Scopus 21
  • ???jsp.display-item.citation.isi??? 19
social impact